A simple, precise and accurate UV Spectrophotometric method have been developed for the simultaneous estimation of Cefixime and Ornidazole in tablet dosage form. The solvent used is 0.1N NaOH. The λmax of Cefixime and Ornidazole was found to be 287 and 318nm. Various validation parameters such as linearity, accuracy, precision were determined as per ICH guidelines. The linearity range was found to be 5-25µg/ml and 5-25µg/ml for Cefixime and Ornidazole respectively. Recovery studies were also carried out and the percent recovery was found to be in the range of 98-102%.Therefore the proposed method can be successfully applied to the routine analysis of both the drugs in quality control laboratories.
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